Dr. M. (Marlies) Wakkee

Research background

Current research interests

Accuracy of a smartphone application for triage of skin lesions based on machine learning algorithms. Udrea A, Mitra GD, Costea D, Noels EC, Wakkee M, Siegel DM, de Carvalho TM, Nijsten TEC. J Eur Acad Dermatol Venereol. 2019 Sep 8. doi: 10.1111/jdv.15935. [Epub ahead of print] PMID: 31494983 [PubMed - as supplied by publisher] Similar articles

 Melanoma in older patients: declining gap in survival between younger and older patients with melanoma. Schuurman MS, Hollestein LM, Bastiaannet E, Posthuma EFM, van Akkooi AJC, Kukutsch NA, Aarts MJB, Wakkee M, Lemmens VEPP, Louwman MWJ. Acta Oncol. 2019 Jul 26:1-9. doi: 10.1080/0284186X.2019.1643914. [Epub ahead of print] PMID: 31347929 [PubMed - as supplied by publisher] Similar articles

Opportunities for improving the efficiency of keratinocyte carcinoma care in primary and specialist care: Results from population-based Dutch cohort studies. Wakkee M, van Egmond S, Louwman M, Bindels P, van der Lei J, Nijsten T, Hollestein L. Eur J Cancer. 2019 Aug;117:32-40. doi: 10.1016/j.ejca.2019.05.010. Epub 2019 Jun 21. PMID: 31229947 [PubMed - in process] Similar articles

Vismodegib for giant, locally advanced, basal cell carcinoma and its complex position in clinical practice. Koekelkoren FHJ, Roodbergen SL, Baerveldt EM, Maat APWM, Monserez DA, Grünhagen DJ, Mureau MAM, de Haas ERM, Nijsten TEC, Wakkee M. JAAD Case Rep. 2019 Mar 1;5(3):267-270. doi: 10.1016/j.jdcr.2018.11.002. eCollection 2019 Mar. No abstract available. PMID: 30891477 [PubMed] Free PMC Article Similar articles

Substitution of low-risk skin cancer hospital care towards primary care: A qualitative study on views of general practitioners and dermatologists. Noels EC, Wakkee M, van den Bos RR, Bindels PJE, Nijsten T, Lugtenberg M. PLoS One. 2019 Mar 19;14(3):e0213595. doi: 10.1371/journal.pone.0213595. eCollection 2019. PMID: 30889211 [PubMed - in process] Free PMC Article Similar articles

Insight into the management of actinic keratosis: a qualitative interview study among general practitioners and dermatologists. Noels EC, Lugtenberg M, van Egmond S, Droger SM, Buis PAJ, Nijsten T, Wakkee M. Br J Dermatol. 2019 Jul;181(1):96-104. doi: 10.1111/bjd.17818. Epub 2019 Mar 15. PMID: 30801664 [PubMed - in process] Free PMC Article Similar articles

Healthcare utilization and management of actinic keratosis in primary and secondary care: a complementary database analysis. Noels EC, Hollestein LM, van Egmond S, Lugtenberg M, van Nistelrooij LPJ, Bindels PJE, van der Lei J, Stern RS, Nijsten T, Wakkee M. Br J Dermatol. 2019 Sep;181(3):544-553. doi: 10.1111/bjd.17632. Epub 2019 Apr 19. PMID: 30636037 [PubMed - in process] Free PMC Article Similar articles

Highlights of the updated Dutch evidence- and consensus-based guideline on psoriasis 2017. van der Kraaij GE, Balak DMW, Busard CI, van Cranenburgh OD, Chung Y, Driessen RJB, de Groot M, de Jong EMGJ, Kemperman PMJH, de Kort WJA, Karsch SA, Lamberts A, Lecluse LLA, van Lümig PPM, Menting SP, Prens EP, van den Reek JMPA, Seyger MMB, Thio HB, Veldkamp WR, Wakkee M, Nast A, Jacobs A, Rosumeck S, Spuls Chair PI. Br J Dermatol. 2019 Jan;180(1):31-42. doi: 10.1111/bjd.17198. No abstract available. PMID: 30604536 [PubMed - in process] Free PMC Article Similar articles

Factors influencing current low-value follow-up care after basal cell carcinoma and suggested strategies for de-adoption: a qualitative study. van Egmond S, Wakkee M, van Rengen A, Bastiaens MT, Nijsten T, Lugtenberg M. Br J Dermatol. 2019 Jun;180(6):1420-1429. doi: 10.1111/bjd.17594. Epub 2019 Mar 28. PMID: 30597525 [PubMed - in process] Free PMC Article Similar articles

Recurrence of periocular basal cell carcinoma and squamous cell carcinoma after Mohs micrographic surgery: a retrospective cohort study. Weesie F, Naus NC, Vasilic D, Hollestein LM, van den Bos RR, Wakkee M. Br J Dermatol. 2019 May;180(5):1176-1182. doi: 10.1111/bjd.17516. Epub 2019 Feb 10. PMID: 30536656 [PubMed - in process] Free PMC Article Similar articles

Recurrence rates of cutaneous squamous cell carcinoma of the head and neck after Mohs micrographic surgery vs. standard excision: a retrospective cohort study. van Lee CB, Roorda BM, Wakkee M, Voorham Q, Mooyaart AL, de Vijlder HC, Nijsten T, van den Bos RR. Br J Dermatol. 2019 Aug;181(2):338-343. doi: 10.1111/bjd.17188. Epub 2018 Oct 28. PMID: 30199574 [PubMed - in process] Similar articles

Psoriasis is not associated with cognition, brain imaging markers and risk of dementia: the Rotterdam Study. Pezzolo E, Mutlu U, Vernooij MW, Dowlatshahi EA, Gisondi P, Girolomoni G, Nijsten T, Ikram MA, Wakkee M. J Am Acad Dermatol. 2018 Aug 6. pii: S0190-9622(18)32348-X. doi: 10.1016/j.jaad.2018.07.046. [Epub ahead of print] PMID: 30092331 [PubMed - as supplied by publisher] Similar articles

Needs and preferences of patients regarding basal cell carcinoma and cutaneous squamous cell carcinoma care: a qualitative focus group study. van Egmond S, Wakkee M, Droger M, Bastiaens MT, van Rengen A, de Roos KP, Nijsten T, Lugtenberg M. Br J Dermatol. 2019 Jan;180(1):122-129. doi: 10.1111/bjd.16900. Epub 2018 Sep 23. PMID: 29927480 [PubMed - in process] Similar articles

Methods report: European S3-Guideline on the systemic treatment of psoriasis vulgaris - Update Apremilast and Secukinumab - EDF in cooperation with EADV and IPC. Dressler C, Rosumeck S, Werner RN, van der Kraaij G, van Lumig P, Wakkee M, Spuls P, Nast A. J Eur Acad Dermatol Venereol. 2017 Dec;31(12):1964-1977. doi: 10.1111/jdv.14470. Epub 2017 Sep 24. No abstract available. PMID: 289445

[PubMed - indexed for MEDLINE] Similar articles 15. The association of autoimmune thyroid disease (AITD) with psoriatic disease: a prospective cohort study, systematic review and meta-analysis. Khan SR, Bano A, Wakkee M, Korevaar TIM, Franco OH, Nijsten TEC, Peeters RP, Chaker L. Eur J Endocrinol. 2017 Oct;177(4):347-359. doi: 10.1530/EJE-17-0397. Epub 2017 Jul 26. Review. PMID: 28747386 [PubMed - indexed for MEDLINE] Similar articles

Smokers versus Smoking: IsThereDetection Bias for Keratinocyte Carcinomas? Wakkee M. J Invest Dermatol. 2017 Aug;137(8):1614-1616. doi: 10.1016/j.jid.2017.05.002. Review. PMID: 28735614 [PubMed - indexed for MEDLINE] Free Article Similar articles

The four Ws of skin cancer surveillance in patients with melanoma: Why? Who? When? Where? Nijsten T, Wakkee M. Br J Dermatol. 2017 Apr;176(4):839-841. doi: 10.1111/bjd.15248. No abstract available. PMID: 28418134 [PubMed - indexed for MEDLINE] Similar articles

Epidemiology of basal cell carcinoma: scholarly review. Verkouteren JAC, Ramdas KHR, Wakkee M, Nijsten T. Br J Dermatol. 2017 Aug;177(2):359-372. doi: 10.1111/bjd.15321. Epub 2017 Feb 20. Review. PMID: 28220485 [PubMed - indexed for MEDLINE] Similar articles

Performance of screening tools for psoriatic arthritis: a cross-sectional study in primary care. Karreman MC, Weel AEAM, van der Ven M, Vis M, Tchetverikov I, Nijsten TEC, Wakkee M, Hazes JMW, Luime JJ. Rheumatology (Oxford). 2017 Apr 1;56(4):597-602. doi: 10.1093/rheumatology/kew410. PMID: 28013202 [PubMed - indexed for MEDLINE] Similar articles

Enhanced liver fibrosis test in patients with psoriasis, psoriatic arthritis and rheumatoid arthritis: a cross-sectional comparison with procollagen-3 N-terminal peptide (P3NP). van der Voort EAM, Wakkee M, Veldt-Kok P, Darwish Murad S, Nijsten T. Br J Dermatol. 2017 Jun;176(6):1599-1606. doi: 10.1111/bjd.15220. Epub 2017 Apr 24. PMID: 27925155 [PubMed - indexed for MEDLINE] Similar articles

Epidemiology of Lentigo Maligna andLentigo Maligna Melanoma in theNetherlands, 1989-2013. Greveling K, Wakkee M, Nijsten T, van den Bos RR, Hollestein LM. J Invest Dermatol. 2016 Oct;136(10):1955-1960. doi: 10.1016/j.jid.2016.06.014. Epub 2016 Jun 24. PMID: 27349862 [PubMed - indexed for MEDLINE] Free Article Similar articles

Rising interest in the field of paediatric psoriasis. Dowlatshahi EA, Wakkee M. Br J Dermatol. 2016 Jun;174(6):1180-1. doi: 10.1111/bjd.14715. No abstract available. PMID: 27317275 [PubMed - indexed for MEDLINE] Similar articles 23. Actinic keratosis in China: big numbers and small percentages. Wakkee M, Nijsten T. Br J Dermatol. 2016 May;174(5):954. doi: 10.1111/bjd.14590. No abstract available. PMID: 27206355 [PubMed - indexed for MEDLINE] Similar articles

Increased overall drug utilization in patients with psoriasis: a case-control study based on Dutch general practitioner data. Dowlatshahi EA, Hollestein LM, Herings RM, Nijsten T, Wakkee M. Br J Dermatol. 2017 Mar;176(3):634-642. doi: 10.1111/bjd.14754. Epub 2016 Oct 12. PMID: 27203361 [PubMed - indexed for MEDLINE] Similar articles

Micrographic surgery of lentigo maligna. van den Bos RR, Wakkee M, Koljenovil S, Nijsten T. Ned Tijdschr Geneeskd. 2016;160:A9827. Dutch. PMID: 27050497 [PubMed - indexed for MEDLINE] Similar articles

Kidney disease in moderate-to-severe psoriasis: commentary. Wakkee M. Br J Dermatol. 2016 Feb;174(2):271-2. doi: 10.1111/bjd.14303. No abstract available. PMID: 26871924 [PubMed - indexed for MEDLINE] Similar articles

Prevalence of Psoriatic Arthritis in Primary Care Patients With Psoriasis. Karreman MC, Weel AE, van der Ven M, Vis M, Tchetverikov I, Nijsten TE, Wakkee M, Hazes JM, Luime JJ. Arthritis Rheumatol. 2016 Apr;68(4):924-31. doi: 10.1002/art.39530. PMID: 26636745 [PubMed - indexed for MEDLINE] Free Article Similar articles

Dermatoepidemiology; what's up people? Nijsten T, Apfelbacher C, Gisondi P, Silverberg J, Cohen A, Barbarot S, Wakkee M, Ezzedine K. Br J Dermatol. 2015 Oct;173(4):881-3. doi: 10.1111/bjd.14100. No abstract available. PMID: 26511819 [PubMed - indexed for MEDLINE] Similar articles

Increased Prevalence of Advanced Liver Fibrosis in Patients with Psoriasis: A Cross-sectional Analysis from the Rotterdam Study. van der Voort EA, Koehler EM, Nijsten T, Stricker BH, Hofman A, Janssen HL, Schouten JN, Wakkee M. Acta Derm Venereol. 2016 Feb;96(2):213-7. doi: 10.2340/00015555-2161. PMID: 26062958 [PubMed - indexed for MEDLINE] Free Article Similar articles

Multivariable analysis. Wakkee M, Hollestein LM, Nijsten T. J Invest Dermatol. 2014 May;134(5):1-5. doi: 10.1038/jid.2014.132. No abstract available. PMID: 24732339 [PubMed - indexed for MEDLINE] Free Article Similar articles

The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: a systematic review and meta-analysis. Dowlatshahi EA, Wakkee M, Arends LR, Nijsten T. J Invest Dermatol. 2014 Jun;134(6):1542-1551. doi: 10.1038/jid.2013.508. Epub 2013 Nov 27. Review. PMID: 24284419 [PubMed - indexed for MEDLINE] Free Article Similar articles

Increased antidepressant drug exposure in psoriasis patients: a longitudinal population-based cohort study. Dowlatshahi EA, Wakkee M, Herings RM, Hollestein LM, Nijsten T. Acta Derm Venereol. 2013 Sep 4;93(5):544-50. doi: 10.2340/00015555-1566. PMID: 23529077 [PubMed - indexed for MEDLINE] Free Article Similar articles

Psoriasis is not associated with atherosclerosis and incident cardiovascular events: the Rotterdam Study. Dowlatshahi EA, Kavousi M, Nijsten T, Ikram MA, Hofman A, Franco OH, Wakkee M. J Invest Dermatol. 2013 Oct;133(10):2347-2354. doi: 10.1038/jid.2013.131. Epub 2013 Mar 14. PMID: 23492918 [PubMed - indexed for MEDLINE] Free Article Similar articles

Is psoriasis a dependent cardiovascular risk factor?. Wakkee M, de Jong EM. Ned Tijdschr Geneeskd. 2013;157(11):A5417. Dutch. PMID: 23484510 [PubMed - indexed for MEDLINE] Similar articles

Increased risk of infectious disease requiring hospitalization among patients with psoriasis: a population-based cohort. Wakkee M, de Vries E, van den Haak P, Nijsten T. J Am Acad Dermatol. 2011 Dec;65(6):1135-44. doi: 10.1016/j.jaad.2010.08.036. Epub 2011 Jun 12. PMID: 21664719 [PubMed - indexed for MEDLINE] Similar articles

Psoriasis and cardiovascular risk: strength in numbers. Gelfand JM, Azfar RS, Mehta NN. J Invest Dermatol. 2010 Apr;130(4):919-22. doi: 10.1038/jid.2010.12. PMID: 20231829 [PubMed - indexed for MEDLINE] Free PMC Article Similar articles

Psoriasis is not a useful independent risk factor for cardiovascular disease. Stern RS. J Invest Dermatol. 2010 Apr;130(4):917-9. doi: 10.1038/jid.2009.446. PMID: 20231828 [PubMed - indexed for MEDLINE] Free Article Similar articles

Psoriasis may not be an independent risk factor for acute ischemic heart disease hospitalizations: results of a large population-based Dutch cohort. Wakkee M, Herings RM, Nijsten T. J Invest Dermatol. 2010 Apr;130(4):962-7. doi: 10.1038/jid.2009.321. Epub 2009 Oct 8. PMID: 19812600 [PubMed - indexed for MEDLINE] Free Article Similar articles

Psoriasis may not be an independent predictor for the use of cardiovascular and anti-diabetic drugs: a 5-year prevalence study. Wakkee M, Meijer W, Neumann HA, Herings RM, Nijsten T. Acta Derm Venereol. 2009;89(5):476-83. doi: 10.2340/00015555-0688. PMID: 19734972 [PubMed - indexed for MEDLINE] Free Article Similar articles

Complexity of the association between psoriasis and comorbidities. Nijsten T, Wakkee M. J Invest Dermatol. 2009 Jul;129(7):1601-3. doi: 10.1038/jid.2009.55. PMID: 19521405 [PubMed - indexed for MEDLINE] Free Article Similar articles